Identifying the Best Haploidentical Donor: Are We There?
نویسندگان
چکیده
منابع مشابه
Selecting the best haploidentical donor.
The substantial evidence of the safety of human leukocyte antigen (HLA)-haploidentical (haplo) blood or marrow transplantation (BMT) has led to its increasing utilization. When prioritizing HLA-matched grafts, patients frequently have few or no donors from whom to choose. However, a given patient may have multiple suitable haplo donors. Therefore factors other than HLA-match become critical for...
متن کاملHow do we choose the best donor for T-cell-replete, HLA-haploidentical transplantation?
In haploidentical stem cell transplantations (haplo-SCT), nearly all patients have more than one donor. A key issue in the haplo-SCT setting is the search for the best donor, because donor selection can significantly impact the incidences of acute and chronic graft-versus-host disease, transplant-related mortality, and relapse, in addition to overall survival. In this review, we focused on fact...
متن کاملHaploidentical transplantation: the search for the best donor.
In this issue of Blood, Wang et al suggest an algorithm for the selection of the best donor in HLA haplotype-mismatched transplantation of T-replete granulocyte colony-stimulating factor (G-CSF)-mobilized bone marrow and peripheral blood stem cells. Donor selection in HLA haplotypemismatched stem cells transplantation might have a significant impact on the development of acute and chronic graft...
متن کاملAre We There Yet?
Children in the back seat on a long trip are not the only ones asking the question “Are we there yet?” At Murray State University (MSU) and other universities starting new programs, the question becomes one of validation of the program. In the late 90s, MSU, a midsize university, was entrusted with the responsibility of developing a program of distinction with financial support from special sta...
متن کاملAre We There Yet?
've always been an avid traveler and often look forward to planning summer trips to faraway destinations. However , whether by train, plane, or automobile , long-distance travel for the majority of us usually comes with some degree of discomfort—long periods of time sitting in a seat with a limited selection of things to do. Fun traveling companions and a good book can help, but faced with a lo...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biology of Blood and Marrow Transplantation
سال: 2018
ISSN: 1083-8791
DOI: 10.1016/j.bbmt.2018.03.003